Job description

ADC (Antibody Drug Conjugate) R&D

Synthesis and purification of complex antibody drug conjugate (ADC) molecules
Synthesis of different type of linkers - using natural and un-natural amino acids, PEGs
Synthesis of high potent drug molecules – payloads
Purification of complex and large molecules by flash column and HPLC
Handling various type chemistry with different payloads
Interpretation and characterization of higher molecular weight compounds
Minimum 3 years in CRO Industry

Synthesis R&D:

Responsible to perform routine organic synthesis. (mg to gram scale) & work independently under the guidance of the leader.
Independently support the scientific team with instrumentation and equipment operation and maintenance.
Able to understand & interpret various instruments like NMR, Mass, HPLC.
Instrument purification like Combiflash, big columns, column packing. Deciding the mobile phase for purification.
Independently handling all types of glassware assembly arrangement, reaction reagent charging, maintaining temperature, nitrogen, etc.
Should be able to understand the written instruction from the scientist including patents and reprints where procedure highlighted by scientists.
To train and support the team members.
Meticulous Documentation & proper data management.
To maintain the record book of the work done like purification or reaction.
1-4 years of experience in CRO Industry

Job requirements

Strong organizational, project management and problem-solving skills with impeccable multi-tasking abilities.

Exceptional interpersonal skills.
Friendly and professional demeanor.
Ability to write reports and prepare spreadsheets and presentations.
Excellent organizational skills with an ability to think proactively and prioritize work.
Proactive, highly motivated with a "can-do" attitude.
Strong and accurate attention to detail.